Cilofexor tromethamine - CAS 2253764-93-9

Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC.

FXR, Autophagy, Others

Metabolism, Autophagy, Others

2253662

C32H33Cl3N4O8

707.99

NC(CO)(CO)CO.OC(=O)c1ccnc(c1)N1CC(O)(C1)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)cc1Cl

-20°C

Ice Packs

Small Compound