Cimiside E - CAS 154822-57-8

Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agent against cancer, it arrests cell cycle and induces cell apoptosis in gastric cancer cells.

TNF, ERK, Caspase, Akt, PI3K, ROS, PKC, PPAR

Cytoskeletal Signaling, Metabolism, MAPK, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Proteases/Proteasome, DNA Damage/DNA Repair, Apoptosis, Immunology/Inflammation

154757

C35H54O8

602.809

[H][C@]12[C@H](C)C[C@H]3O[C@@]1(O[C@H]3C(C)=C)[C@H](O)[C@@]1(C)[C@]3([H])CC[C@]4([H])[C@]5(C[C@@]35CC[C@]21C)CC[C@H](O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)C4(C)C

-20°C

Ice Packs

Natural Product