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Ciprostene (free base) - CAS 81845-44-5
Ciprostene (free base) - CAS 81845-44-5
SKU:MF-0143449-01
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Product Details
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Bioactivity
Ciprostene (free base) is a synthetic, chemically stable analog of prostacyclin (PGI2) . In animal models, administration of ciprostene resulted in dose-dependent hypotension, tachycardia, and inhibition of ex vivo ADP-induced platelet aggregation. Ciprostene was evaluated in clinical trials in patients with peripheral vascular disease. It was found to reduce restenosis in patients with coronary artery disease undergoing therapeutic percutaneous transluminal coronary angioplasty.
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Target
Prostaglandin Receptor, Others
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Related Pathways
GPCR/G Protein, Others, Immunology/Inflammation
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CAS Number
81796
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Molecular Formula
C22H36O4
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Molecular Weight
364.52
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SMILES
C[C@@]12[C@@]([C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1)(C\C(=C\CCCC(O)=O)\C2)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound