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Ciprostene (free base) - CAS 81845-44-5

Ciprostene (free base) - CAS 81845-44-5

SKU:MF-0143449-01

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  • Bioactivity

    Ciprostene (free base) is a synthetic, chemically stable analog of prostacyclin (PGI2) . In animal models, administration of ciprostene resulted in dose-dependent hypotension, tachycardia, and inhibition of ex vivo ADP-induced platelet aggregation. Ciprostene was evaluated in clinical trials in patients with peripheral vascular disease. It was found to reduce restenosis in patients with coronary artery disease undergoing therapeutic percutaneous transluminal coronary angioplasty.

  • Target

    Prostaglandin Receptor, Others

  • Related Pathways

    GPCR/G Protein, Others, Immunology/Inflammation

  • CAS Number

    81796

  • Molecular Formula

    C22H36O4

  • Molecular Weight

    364.52

  • SMILES

    C[C@@]12[C@@]([C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1)(C\C(=C\CCCC(O)=O)\C2)[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound