Cisd2 agonist 2 - CAS 2916371-59-8

Cisd2 agonist 2 (compound 6), with an EC50 of 191 nM, is an orally active activator of Cisd2, a protein whose levels are associated with nonalcoholic fatty liver disease (NAFLD) . In vivo studies have demonstrated that Cisd2 agonist 2 exhibits no significant toxicity in heterozygous hepatocyte-specific Cisd2 knockout (Cisd2hKO-het) mice [1].

Others, IKZF

Others, Immunology/Inflammation

2916371-59-8

C14H14N2O4S

306.34

O=C(OC)C1=C(SC(C(=O)NC2=CC=C(O)C=C2)=C1C)N

-20°C

Ice Packs

Small Compound