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Cisplatin/Dasatinib prodrug-1 - CAS 3049801-09-1
Cisplatin/Dasatinib prodrug-1 - CAS 3049801-09-1
SKU:MF-0117506-01
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Product Details
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Bioactivity
Cisplatin/Dasatinib prodrug-1 (Compound 3) is a precursor drug for Cisplatin and Dasatinib. It exhibits antiproliferative activity against tumor cell lines A2780, MDA-MB-231, MCF7, HCT116, RD, Thp1, and HL60, with IC50 values of 0.1, 0.1, 0.36, 2.0, 0.4, 0.3, and 0.25 μM, respectively.
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Target
Src
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Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
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CAS Number
3049801-09-1
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Molecular Formula
C33H42Cl3N9O6PtS
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Molecular Weight
994.25
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SMILES
O=C(OCCN1CCN(C=2N=C(N=C(C2)NC3=NC=C(S3)C(=O)NC=4C(Cl)=CC=CC4C)C)CC1)[O-][Pt+4]([Cl-])([Cl-])([O-]C(=O)CCCC=5C=CC=CC5)([NH3])[NH3]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound