CJ-15208 - CAS 210236-47-8

CJ-15208 is a potent and selective κ-opioid receptor antagonist from a fungus, Ctenomyces serratus ATCC15502 (IC50 are 47 nM for kappa, 260 nM for mu, and 2,600 nM for delta respectly) . In the electrically-stimulated twitch response assay of rabbit vas deferens, CJ-15208 recovered the suppression by a kappa agonist asimadoline with an ED50 of 1.3 microM.

Others, Opioid Receptor

Endocrinology/Hormones, Neuroscience, GPCR/G Protein, Others

210181

C34H35N5O4

577.67

C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N5[C@@](C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N3)(CCC5)[H]

-20°C

Ice Packs

Small Compound