CK1δ-IN-9 - CAS 3057263-82-5

CK1δ-IN-9 (Compound 8) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ with an IC50 of 1.4 nM. The compound also inhibits p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 exhibits favorable pharmacokinetic properties, including high oral bioavailability (70%) and moderate clearance.

Casein Kinase, p38 MAPK

MAPK, Stem Cells, Metabolism

3057176

C16H12FN5

293.298

FC=1C=CC(=CC1)C2=NN(C=C2C=3C=CN=C4NN=CC43)C

-20°C

Ice Packs

Small Compound