CK2-IN-9 - CAS 1461658-58-1

CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter activity with an IC50 of 75 nM. In rats, it demonstrates low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) [1].

Others, Casein Kinase, Wnt/beta-catenin

Stem Cells, Metabolism, Others, Cytoskeletal Signaling

1461599

C23H29N9O

447.54

C(#N)C1=C2N(C(NC3CC3)=CC(NC4=CC(NC(C)=O)=C(N(CCN(C)C)C)C=C4)=N2)N=C1

-20°C

Ice Packs

Small Compound