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Molfinity

CL4F8-6 - CAS 2766493-12-1

CL4F8-6 - CAS 2766493-12-1

MF-0120080-01

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Product Details

  • Bioactivity

    CL4F8-6, an ionizable cationic lipid with a pKa of 6.14, is utilized in lipid nanoparticles (LNPs) for mRNA therapeutics. When incorporated into LNPs delivering Cas9 mRNA and sgRNA, CL4F8-6 facilitates CRISPR-mediated gene knockdown in mice [1].

  • Target

    Others, Liposome

  • Related Pathways

    Metabolism, Others

  • CAS Number

    2766493-12-1

  • Molecular Formula

    C51H101NO5

  • Molecular Weight

    808.35

  • SMILES

    C(CCCCN(CCC)CCC)(CCCCCCOC(C(CCCCCC)CCCCCC)=O)(CCCCCCOC(C(CCCCCC)CCCCCC)=O)O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Inhibitors & Agonists