Clematomandshurica saponin B - CAS 916649-91-7

Clematomandshurica saponin B shows significant inhibitory activity on cyclooxygenase-2 (IC50 = 2.58 microM) .

COX

Immunology/Inflammation, Neuroscience

916551

C92H142O46

1984.08

C(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@]45[C@](C=6[C@@](C)(CC4)[C@@]7(C)[C@](CC6)([C@]8(C)[C@@](CC7)(C(C)(C)[C@@H](O[C@H]9[C@H](O[C@H]%10[C@H](O)[C@H](O[C@H]%11[C@H](O)[C@H](O)[C@H](O[C@@H]%12O[C@H](CO)[C@@H](O[C@H]%13[C@H](OC(/C=C/C%14=CC(O)=C(OC)C=C%14)=O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]%15[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O%15)O%13)[C@H](O)[C@H]%12O)CO%11)[C@@H](O)[C@H](C)O%10)[C@@H](O)[C@@H](O)CO9)CC8)[H])[H])(CC(C)(C)CC5)[H]

-20°C

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Natural Product