CLM296 - CAS 3067837-25-3

CLM296 is a potent and selective inhibitor of ALDH1A3, with an IC50 of 2 nM. It does not exhibit off-target effects on the highly homologous ALDH1A1 isoform. CLM296 is capable of inhibiting ALDH1A3-driven breast cancer metastasis and can be utilized in the study of triple-negative breast cancer (TNBC) .

Dehydrogenase

Metabolism

3067809

C29H22N2O2

430.5

O=C(C=1C=CC(=CC1)C=2C=C(C=3C=CC(=CC3)C(=O)C)C4=NC(=CN4C2)C=5C=CC=CC5)C

-20°C

Ice Packs

Small Compound