Clofarabine - CAS 123318-82-1

Clofarabine (Clofarex) m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.

Apoptosis, Nucleoside Antimetabolite/Analog, Autophagy, DNA/RNA Synthesis

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Autophagy, Apoptosis

123235

>99.99%

C10H11ClFN5O3

303.68

Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F

-20°C

Ice Packs

Small Compound