Clofarabine-5'-triphosphate - CAS 134646-41-6

Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK) . It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.

DNA/RNA Synthesis

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

134599

C10H14ClFN5O12P3

543.62

F[C@@H]1[C@H](N2C=3C(N=C2)=C(N)N=C(Cl)N3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O

-20°C

Ice Packs

Small Compound