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Clonixeril - CAS 21829-22-1
Clonixeril - CAS 21829-22-1
SKU:MF-0118100-01
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Product Details
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Bioactivity
Clonixeril (NSC 335504) is a non-nucleotide modulator of hSTING. It exhibits weak agonistic activity at micromolar concentrations and can antagonize the hSTINGWT pathway at low femtomolar (10^-15 M) and even attomolar (10^-18 M) concentrations in some cases. Clonixeril inhibits hSTING oligomerization at concentrations ranging from 1 aM to 1 pM.
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Target
STING
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Related Pathways
Immunology/Inflammation
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CAS Number
21806
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Molecular Formula
C16H17ClN2O4
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Molecular Weight
336.77
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SMILES
O=C(OCC(O)CO)C1=CC=CN=C1NC=2C=CC=C(Cl)C2C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound