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Molfinity

CLZ-8 - CAS 678158-55-9

CLZ-8 - CAS 678158-55-9

MF-0033410

$42.14 USD
$42.14 USD
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Product Details

  • Bioactivity

    CLZ-8 (Mcl1-IN-8) is an orally active inhibitor of Mcl-1-PUMA (p53 up-regulated mediator of apoptosis) with radioprotective properties.CLZ-8 ameliorates radiation-induced HUVEC cell damage and reduces apoptosis counts, and inhibits radiation-induced overexpression of PUMA.

  • Target

    Apoptosis, Bcl-2 Family

  • Related Pathways

    Apoptosis

  • CAS Number

    678094

  • Purity

    0.9985

  • Molecular Formula

    C22H23N3O2S

  • Molecular Weight

    393.5

  • SMILES

    OCCN1CCN(CC1)C1=NC(=O)\C(S1)=C\c1ccc(cc1)-c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound