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CMP3a - CAS 2225902-88-3
CMP3a - CAS 2225902-88-3
SKU:MF-0142146-01
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$1,647.05 USD
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$1,647.05 USD
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Product Details
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Bioactivity
CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
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Target
MAPK, Others
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Related Pathways
MAPK, Others
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CAS Number
2225811
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Molecular Formula
C28H27F3N6O2S
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Molecular Weight
568.61
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SMILES
O([C@@H](C)C1=C(C(F)(F)F)C=CC=C1)C=2C=C(C=3N4C(=NC3)C=C(C=C4)C5=CN(CCN(C)C)N=C5)SC2C(N)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound