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CMPD101 hydrochloride - CAS 1941168-71-3

CMPD101 hydrochloride - CAS 1941168-71-3

MF-0122176-01

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Product Details

  • Bioactivity

    CMPD101 hydrochloride is a membrane-permeable small molecule inhibitor of GRK2 and GRK3, exhibiting IC50 values of 18 nM and 5.4 nM, respectively. This compound also inhibits Rho-associated kinase 2 (ROCK-2) and PKCα, with IC50 values of 1.4 μM and 8.1 μM, respectively.

  • CAS Number

    1941168-71-3

  • Molecular Formula

    C24H22ClF3N6O

  • Molecular Weight

    502.92

  • SMILES

    Cl.O=C(NCC=1C=CC=CC1C(F)(F)F)C=2C=CC=C(C2)NCC3=NN=C(C=4C=CN=CC4)N3C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound