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Molfinity

COB-187 - CAS 1862177-86-3

COB-187 - CAS 1862177-86-3

MF-0121813-01

$901.17 USD
$901.17 USD
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Product Details

  • Bioactivity

    COB-187 is an effective, ATP-competitive, selective inhibitor of GSK-3β. It inhibits GSK-3 through a reversible, cysteine (Cys) -199 dependent mechanism. Additionally, COB-187 suppresses the production of cytokines induced by LPS and the production of CXCL10 triggered by the SARS-CoV-2 spike protein.

  • Target

    GSK-3

  • Related Pathways

    PI3K/Akt/mTOR signaling, Stem Cells

  • CAS Number

    1862177-86-3

  • Molecular Formula

    C15H14N2OS2

  • Molecular Weight

    302.41

  • SMILES

    S=C1SCC(O)(C=2C=CC=CC2)N1CC=3C=CN=CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound