Coccinine - CAS 485-57-4

Coccinine ((-) -Coccinine) is a weak inhibitor of SERT with an IC50 of 196.3 μM and a Ki of 106.8 μM, and P-gp with an IC50 of 0.96 mM. It demonstrates significant antitumor activity against various cancer cell lines, including breast cancer (MCF7, Hs578T, MDA-MB-231), colon cancer (HCT-15), and lung cancer (A549) . Additionally, Coccinine is applicable in research involving tumors and neurological disorders.

Serotonin Transporter, P-gp

Membrane transporter/Ion channel, Neuroscience

485-57-4

C17H19NO4

301.34

O(C)[C@@H]1C=C2[C@@]3(C=4C(C[N@@](C3)[C@]2(C[C@@H]1O)[H])=CC5=C(C4)OCO5)[H]

-20°C

Ice Packs

Natural Product