Cochliodone A - CAS 1072931-48-6

Cochliodone A, a bioactive compound isolated from the deep-sea fungus Chaetomium sp., exhibits both antibacterial and anticancer properties. This substance demonstrates toxicity against multiple bacterial strains, as evidenced by its minimum inhibitory concentrations (MICs) of 15.3 μg/mL for V. vulnificus, 32.7 μg/mL for V. rotiferianus, 15.9 μg/mL for S. aureus ATCC 43300, and 16.3 μg/mL for S. aureus CGMCC 1.12409. Additionally, Cochliodone A effectively inhibits several cancer cell lines, with half-maximal inhibitory concentrations (IC50s) recorded at 28.1 μM for A549, 20.7 μM for HeLa, and 23.2 μM for Hep G2 [1].

Others, Antibacterial

Microbiology/Virology, Others

1072877

C34H38O12

638.66

O=C1C(=C2C(C(=O)C1(OC(C)=O)C)=COC3(C2)OC(C)CCC3)C4=C5C(C(=O)C(OC(C)=O)(C)C4=O)=COC6(C5)OC(C)CCC6

-20°C

Ice Packs

Small Compound