Coenzyme Q0 - CAS 605-94-7

Coenzyme Q0 (CoQ0), a potent, orally active ubiquinone compound derived from Antrodia cinnamomea, induces apoptosis and autophagy. It suppresses HER-2/AKT/mTOR signaling, enhancing apoptosis and autophagy mechanisms. Additionally, Coenzyme Q0 regulates NFκB/AP-1 activation and promotes Nrf2 stabilization, contributing to the attenuation of inflammation and redox imbalance. It also exhibits anti-angiogenic activity by downregulating MMP-9/NF-κB and upregulating HO-1 signaling.

Others, ROS, Interleukin, mTOR, MMP, COX, Autophagy, EGFR, Reactive Oxygen Species, Caspase, NF-κB, PARP, Akt, Bcl-2 Family, Apoptosis, TNF, NO Synthase

JAK/STAT signaling, PI3K/Akt/mTOR signaling, NF-κB, Tyrosine Kinase/Adaptors, Angiogenesis, Others, DNA Damage/DNA Repair, Apoptosis, Metabolism, Autophagy, Neuroscience, Cytoskeletal Signaling, Chromatin/Epigenetic, Immunology/Inflammation, Proteases/Proteasome

504

C9H10O4

182.17

COC1=C(OC)C(=O)C(C)=CC1=O

-20°C

Ice Packs

Natural Product