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COH34 - CAS 906439-72-3
COH34 - CAS 906439-72-3
SKU:MF-0021965-01
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$59.34 USD
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$59.34 USD
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Product Details
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Bioactivity
COH34 (1-[ (E) - (4-methylphenyl) sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.
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Target
Others, Poly (ADP-ribose) Glycohydrolase (PARG)
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Related Pathways
Cell Cycle/Checkpoint, Others
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CAS Number
906364
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Purity
0.9957
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Molecular Formula
C18H15NOS
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Molecular Weight
293.38
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SMILES
Cc1ccc(S\N=C\c2c(O)ccc3ccccc23)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound