Collagen-IN-1 - CAS 104260-73-3

Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative that selectively inhibits collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Collagen-IN-1 reduces P-selectin expression, glycoprotein IIb/IIIa activation, and the release of adenosine triphosphate and CD63 from platelets. This compound is promising for research into platelet-related thrombosis diseases [1].

Others

Others

104184

C14H14O3

230.26

OC1=C2C3(C=CC(=O)C2=C(O)C=C1)CCCC3

-20°C

Ice Packs

Small Compound