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Combretastatin A-1 - CAS 109971-63-3
Combretastatin A-1 - CAS 109971-63-3
SKU:MF-0094134-01
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$36.16 USD
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$36.16 USD
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Product Details
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Bioactivity
Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and can be used to study hepatocellular carcinoma.
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Target
Akt, Microtubule Associated, Wnt/beta-catenin
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Related Pathways
Cytoskeletal Signaling, Stem Cells, PI3K/Akt/mTOR signaling
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CAS Number
109905
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Purity
0.9749
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Molecular Formula
C18H20O6
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Molecular Weight
332.35
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SMILES
COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)c(O)c1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound