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Combretastatin A-1 - CAS 109971-63-3

Combretastatin A-1 - CAS 109971-63-3

SKU:MF-0094134-01

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  • Bioactivity

    Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and can be used to study hepatocellular carcinoma.

  • Target

    Akt, Microtubule Associated, Wnt/beta-catenin

  • Related Pathways

    Cytoskeletal Signaling, Stem Cells, PI3K/Akt/mTOR signaling

  • CAS Number

    109905

  • Purity

    0.9749

  • Molecular Formula

    C18H20O6

  • Molecular Weight

    332.35

  • SMILES

    COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)c(O)c1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound