Combretastatin A-1 phosphate tetrasodium - CAS 288847-34-7

Combretastatin A-1 phosphate (OXi-4503) tetrasodium, a prodrug of Combretastatin A-1, is a tubulin-binding microtubule polymerization inhibitor targeting the colchicine-binding site. By inducing tubulin depolymerization, it inhibits the Wnt/β-catenin pathway and deactivates AKT, possessing both anti-tumor and anti-vascular properties.

Others, Microtubule Associated, Wnt/beta-catenin

Stem Cells, Others, Cytoskeletal Signaling

288806

C18H18Na4O12P2

580.24

[Na].COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)c(OP(O)(O)=O)c1OP(O)(O)=O

-20°C

Ice Packs

Small Compound