Conatumumab - CAS 896731-82-1

Conatumumab (AMG 655) is a monoclonal agonist antibody targeting human death receptor 5 [DR5, TRAILR2] with a dissociation constant (Kd) of 1 nM for long DR5 and 0.8 nM for short DR5. It induces apoptosis in various tumor types through caspase activation and can be used to study advanced solid tumors.

TNF

Apoptosis

896648

>95%

-20°C

Ice Packs

Inhibitory Antibodies