Connexin mimetic peptide 40GAP27 - CAS 403858-30-0

Connexin mimetic peptide 40GAP27, corresponding to the GAP27 domain of the second extracellular loop of the dominant vascular connexin (Cx40), designated as 40Gap27, is a biologically active peptide utilized to study the pathways by which oxidant stress hinders gap junction communication. Administered 40Gap27 attenuates endothelium-dependent subintimal smooth muscle hyperpolarization.

Gap Junction Protein

Cytoskeletal Signaling

403858-30-0

C58H96N16O17

1289.48

C([C@@H](NC([C@H](CO)N)=O)CCCNC(=N)N)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)[C@H](CC)C)=O)=O)C(C)C)=O)CC(N)=O)=O)CCCCN)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CCC1

-20°C

Ice Packs

Peptide