α-Conotoxin AuIA - CAS 216299-20-6

α-Conotoxin AuIA, isolated from Conus aulicus [1], is a potent and selective inhibitor of α3β4 nicotinic acetylcholine receptors (nAChRs) .

AChR

Neuroscience

216273

C72H96N18O24S4

1725.9

O=C1[C@]2(N(C(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CO)NC(=O)[C@]4(NC(=O)[C@@H](NC(CN)=O)CSSC[C@](NC(=O)[C@]5(N1CCC5)[H])(C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N[C@@H](C)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC7=CC=C(O)C=C7)C(=O)N[C@H](C(N)=O)CSSC4)[H])[H])[H])CCC2)[H]

-20°C

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Peptide