α-Conotoxin PeIA - CAS 866876-88-2

α-Conotoxin PeIA is an analgesic that inhibits nAChRs α6β4, α9α10, and α3β2, and potently inhibits the N-type calcium channel through GABAB receptor activation [1] [2] [3].

GABA Receptor, AChR, Calcium Channel

Neuroscience, Membrane transporter/Ion channel, Metabolism

866786

C65H98N22O21S4

1651.87

O=C1N2[C@](C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N)=O)CSSC[C@@]3(NC(=O)[C@@H](NC(CN)=O)CSSC[C@@](C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H]1CC4=CN=CN4)(NC(=O)[C@H](C)NC(=O)[C@]5(N(C(=O)[C@H](CC6=CN=CN6)NC(=O)[C@H](CO)NC3=O)CCC5)[H])[H])[H])(CCC2)[H]

-20°C

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Peptide