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Conteltinib - CAS 1384860-29-0

Conteltinib - CAS 1384860-29-0

SKU:MF-0032631-01

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  • Bioactivity

    Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma.

  • Target

    FAK, PYK2, ALK

  • Related Pathways

    Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

  • CAS Number

    1384831

  • Purity

    0.9954

  • Molecular Formula

    C32H45N9O3S

  • Molecular Weight

    635.82

  • SMILES

    COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCC(CC1)N1CCN(C)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound