COP1-ATGL modulator 1 - CAS 2946701-09-1

COP1-ATGL modulator 1 (86) is an orally active compound that targets the COP1-ATGL axis. It enhances ATGL protein expression, decreases ATGL ubiquitination and COP1 autoubiquitination, and notably reduces lipid accumulation in hepatocytes, effective in the nanomolar concentration [1].

E1/E2/E3 Enzyme, Lipase, Others

Metabolism, Others, Ubiquitination

2946701-09-1

C27H33N5O5

507.58

C(CN1CCCCC1)N2C=3C(C(=O)N(CCOC)C2=O)=CC(NC(NC4=CC(C(C)=O)=CC=C4)=O)=CC3

-20°C

Ice Packs

Small Compound