Coronarin D - CAS 119188-37-3

Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active against tested Gram-positive bacteria, inactive for tested Gram-negative bacteria, and weakly active against tested fungi; using coronarin D-antibiotic drug combination can combat the infectious diseases.Coronarin D inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.

Bcl-2 Family, c-Myc, NF-κB, Caspase, Antifection, COX, TNF

Microbiology/Virology, Proteases/Proteasome, Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint, Neuroscience, NF-κB

119188-37-3

C20H30O3

318.457

CC1(C)CCCC2(C)C(CC=C3CC(O)OC3=O)C(=C)CCC12 |w:10.9|

-20°C

Ice Packs

Natural Product