α-Cortolone - CAS 516-42-7

α-Cortolone, a metabolite of the glucocorticoid cortisol (hydrocortisone), is produced through the action of 20α-hydroxysteroid dehydrogenase (20α-HSD) via a tetrahydrocortisone (THE) intermediate. Studies indicate that urinary levels of α-cortolone are reduced in patients experiencing severe anorexia nervosa and postmenopausal women diagnosed with endometrial adenocarcinoma, in comparison to postmenopausal women without the condition.

Others, Glucocorticoid Receptor

Endocrinology/Hormones, Others

516-42-7

C21H34O5

366.49

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-20°C

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Small Compound