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COX-2/15-LOX-IN-1 - CAS 2413565-15-6
COX-2/15-LOX-IN-1 - CAS 2413565-15-6
SKU:MF-0139328-01
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Product Details
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Bioactivity
COX-2/15-LOX-IN-1 (Compound 14) is a dual inhibitor of COX-2 and 15-lipoxygenase (15-LOX) with IC50 values of 10.65 μM for COX-1, 0.075 μM for COX-2, and 2.98 μM for 15-LOX, exhibiting an anti-inflammatory effect.
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Target
Others, Lipoxygenase, COX
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Related Pathways
Neuroscience, Metabolism, Immunology/Inflammation, Others
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CAS Number
2413544
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Molecular Formula
C21H21N7S3
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Molecular Weight
467.63
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SMILES
S(C)C=1N(C=2C(N1)=CC=CC2)C=3N=C(NCC(=NNC(NC4=CC=CC=C4)=S)C)SC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound