COX-2/5-LOX-IN-1 - CAS 2410384-50-6

COX-2/5-LOX-IN-1 (compound 3a), a benzothiophen-2-yl pyrazole carboxylic acid derivative, is a potent dual inhibitor of COX-2 and 5-LOX, exhibiting superior analgesic and anti-inflammatory properties compared to Celecoxib and Indomethacin. It demonstrates strong inhibitory activity against COX-1, COX-2, and 5-LOX, with IC50 values of 12.13 μM, 0.4 μM, and 4.96 μM, respectively [1].

Others, COX

Immunology/Inflammation, Others, Neuroscience

2410328

C14H10ClN3O4S2

383.83

C(O)(=O)C=1C=C(N(N1)C2=CC=C(S(N)(=O)=O)C=C2)C=3SC(Cl)=CC3

-20°C

Ice Packs

Small Compound