COX-2/5-LOX-IN-2 - CAS 2410384-59-5

COX-2/5-LOX-IN-2 is a benzothiophen-2-ylpyrazole carboxylic acid derivative that inhibits both COX-2 and 5-LOX. COX-2/5-LOX-IN-2 (5b) has IC50 values of 5.40, 0.01, and 1.78 μM for COX-1, COX-2, and 5-LOX, respectively, and exhibits greater analgesic and anti-inflammatory activities than Celecoxib and Indomethacin.

COX, Others

Immunology/Inflammation, Neuroscience, Others

2410320

C18H13N3O4S2

399.44

C(O)(=O)C=1C=C(N(N1)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC=4C(S3)=CC=CC4

-20°C

Ice Packs

Small Compound