COX-2/5-LOX-IN-3 - CAS 2481484-51-7

COX-2/5-LOX-IN-3 (compound 5b) is a powerful dual inhibitor of COX-2 and 5-LOX, with IC50 values of 45.73 μM, 5.45 μM, and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively, showing promise for the investigation of inflammatory diseases [1].

Others, COX, Lipoxygenase

Others, Metabolism, Immunology/Inflammation, Neuroscience

2481426

C17H16ClN3O2S

361.85

C(#N)C=1C(=CSC1NC(CN2CCOCC2)=O)C3=CC=C(Cl)C=C3

-20°C

Ice Packs

Small Compound