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COX-2-IN-14 - CAS 2428387-48-6

COX-2-IN-14 - CAS 2428387-48-6

MF-0006523-01

$1,383.80 USD
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Product Details

  • Bioactivity

    COX-2-IN-14 (compound 2a) is a highly potent and selective inhibitor of COX-2 (cyclooxygenase-2), binding strongly at the active site of the COX-2 co-crystal. Demonstrating remarkable in vivo anti-inflammatory activity, COX-2-IN-14 effectively reduces ear edema and myeloperoxidase (MPO) activity in mice [1].

  • Target

    Others, COX

  • Related Pathways

    Others, Neuroscience, Immunology/Inflammation

  • CAS Number

    2428387-48-6

  • Molecular Formula

    C18H18N4O6

  • Molecular Weight

    386.364

  • SMILES

    CNC.CCOC(=O)c1[nH]c(=O)c(cc1C(=O)c1ccc(cc1)[N+]([O-])=O)C#N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound