COX-2-IN-32 - CAS 2725863-08-9

COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2 that downregulates NF-κB expression and demonstrates anti-inflammatory properties by impeding NO production in LPS-induced RAW264.7 macrophages with an IC50 value of 11.2 μM [1].

COX, NF-κB, NO Synthase

Neuroscience, NF-κB, Immunology/Inflammation

2725863-08-9

C25H24O6

420.45

C(/C=C/C1=CC=C(OC2=CC=C(OC)C=C2)C=C1)(=O)C3=CC(OC)=C(OC)C(OC)=C3

-20°C

Ice Packs

Small Compound