COX-2/sEH-IN-1 - CAS 2474977-38-1

COX-2/sEH-IN-1 is an orally active dual inhibitor of COX-2 (IC50: 1.24 μM) and sEH (IC50: 0.40 μM), a soluble epoxide hydrolase. COX-2/sEH-IN-1 increases anti-inflammatory effects and significantly reduces cardiovascular risk.

Epoxide Hydrolase, Others, COX

Others, Metabolism, Immunology/Inflammation, Neuroscience

2474938

C23H18F3N5O3S

501.48

N(C(NC1=CC=C(C(F)(F)F)C=C1)=O)C2=NN(C(=C2)C3=CC=CC=C3)C4=CC=C(S(N)(=O)=O)C=C4

-20°C

Ice Packs

Small Compound