CP-10 - CAS 2366268-80-4

CP-10 is a PROTAC with highly selective and remarkable CDK6 degradation (DC50: 2.1 nM) . It inhibits the proliferation of several hematopoietic cancer cells including multiple myeloma and can degrade mutated and overexpressed CDK6.

PROTACs, CDK

PROTAC, Cell Cycle/Checkpoint

2366184

C44H49N13O7

871.94

O=C1C=2C=CC=C(NCCOCCN3N=NC(=C3)CN4CCN(C5=CN=C(C=C5)NC=6N=CC7=C(N6)N(C(=O)C(C(=O)C)=C7C)C8CCCC8)CC4)C2C(=O)N1C9C(=O)NC(=O)CC9

-20°C

Ice Packs

PROTAC