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CP-100356 hydrochloride - CAS 142715-48-8

CP-100356 hydrochloride - CAS 142715-48-8

SKU:MF-0046659

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  • Bioactivity

    CP-100356 hydrochloride is an orally active, low micromolar dual inhibitor of MDR1 (P-gp) and BCRP, a nucleotide-derived substrate analogue that inhibits MDR1-mediated Calcein-AM and BCRP-mediated Prazosin transporters. Additionally, CP-100356 inhibits OATP1B1 and induces stomatal opening in the dark.

  • Target

    P-gp, BCRP

  • Related Pathways

    Neuroscience, Membrane transporter/Ion channel

  • CAS Number

    142659

  • Purity

    0.9919

  • Molecular Formula

    C31H37ClN4O6

  • Molecular Weight

    597.1

  • SMILES

    Cl.COc1ccc(CCNc2nc(N3CCc4cc(OC)c(OC)cc4C3)c3cc(OC)c(OC)cc3n2)cc1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound