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CP 122721 hydrochloride - CAS 145877-52-7
CP 122721 hydrochloride - CAS 145877-52-7
SKU:MF-0120128-01
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Product Details
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Bioactivity
CP 122721 hydrochloride is a potent and selective non-peptide (nonpeptide) neurokinin NK1 antagonist, demonstrating a pIC50 of 9.8 against the human NK1 receptor in IM-9 cells. It exhibits anxiolytic and antidepressant-like effects, as evidenced in studies [1] [2].
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Target
Others, Neurokinin receptor
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Related Pathways
Neuroscience, GPCR/G Protein, Others
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CAS Number
145877-52-7
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Molecular Formula
C20H25Cl2F3N2O2
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Molecular Weight
453.33
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SMILES
N(CC1=C(OC)C=CC(OC(F)(F)F)=C1)[C@@H]2[C@@H](NCCC2)C3=CC=CC=C3.Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound