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CP-547632 - CAS 252003-65-9
CP-547632 - CAS 252003-65-9
SKU:MF-0006646-01
Regular price
$32.42 USD
Regular price
$19.50 USD
Sale price
$32.42 USD
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Product Details
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Bioactivity
CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRβ and related tyrosine kinases (TKs) . PDGFRβ and related tyrosine kinases (TKs) CP-547632 has antitumour activity.
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Target
PDGFR, BTK, FGFR, VEGFR
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Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
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CAS Number
252003-65-9
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Purity
0.9939
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Molecular Formula
C20H24BrF2N5O3S
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Molecular Weight
532.4
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SMILES
NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound