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CP-547632 TFA - CAS 2805804-54-8
CP-547632 TFA - CAS 2805804-54-8
SKU:MF-0146800-01
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$1,778.67 USD
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$1,778.67 USD
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Product Details
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Bioactivity
CP-547632 TFA is an orally active, ATP-competitive inhibitor that potently targets VEGFR-2 and FGF kinases with IC50 values of 11 nM and 9 nM, respectively. It demonstrates selectivity for VEGFR-2 and bFGF over EGFR, PDGFRβ, and related tyrosine kinases (TKs), exhibiting antitumor efficacy [1].
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Target
FGFR, VEGFR
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Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
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CAS Number
2805742
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Molecular Formula
C22H25BrF5N5O5S
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Molecular Weight
646.43
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound