CPD-10 - CAS 3055471-57-0

CPD-10 is a potent bifunctional PROTAC degrader targeting CCND1 and CDK4 and exhibits antiproliferative effects. It induces apoptosis and reduces the protein expression of Cyclin D1, Cyclin D3, CDK4, and P-Rb (5807/811) in a dose-dependent manner.

Apoptosis, PROTACs, Glucocorticoid Receptor, CDK

PROTAC, Endocrinology/Hormones, Apoptosis, Cell Cycle/Checkpoint

3055414

C46H61N15O4

888.08

O=C(NC1=NN=C(C=C1)N(C)C)C2=CC=C(N=C2NCCCCCCCNC(=O)CN3CCN(C4=CN=C(C=C4)NC=5N=CC6=C(N5)N(C(=O)C(C(=O)C)=C6C)C7CCCC7)CC3)NC

-20°C

Ice Packs

PROTAC