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CPD-1224 - CAS 2891620-68-9
CPD-1224 - CAS 2891620-68-9
SKU:MF-0155157-01
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Product Details
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Bioactivity
CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R.
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Target
Others, ALK
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Related Pathways
Others, Tyrosine Kinase/Adaptors, Angiogenesis
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CAS Number
2891543
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Molecular Formula
C43H47ClN8O7S
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Molecular Weight
855.4
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SMILES
O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CC(C4)CN5CCC(C6=CC(OC)=C(C=C6C)NC7=NC=C(Cl)C(=N7)NC=8C=CC=CC8S(=O)(=O)C(C)C)CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound