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CPI-455 HCl - CAS 2095432-28-1
CPI-455 HCl - CAS 2095432-28-1
SKU:MF-0139881-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with targeted agents or standard chemotherapy.
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Target
Histone Demethylase
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Related Pathways
Chromatin/Epigenetic
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CAS Number
2095403
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Molecular Formula
C16H15ClN4O
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Molecular Weight
314.77
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SMILES
Cl.CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound