CPS2 - CAS 2756741-90-7

CPS2, a first-in-class, highly potent, selective, and irreversible PROTAC CDK2 degrader (IC 50 = 24 nM), is utilized in the research of acute myeloid leukemia [1].

PROTACs, CDK

PROTAC, Cell Cycle/Checkpoint

2756644

C38H42N12O10S2

890.94

Cc1ccsc1C(=O)n1nc(Nc2ccc(cc2)S(=O)(=O)NCCOCc2cn(CCOCCOCCNc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)nn2)nc1N

-20°C

Ice Packs

Small Compound