CPUL1 - CAS 2043660-80-4

CPUL1, a TrxR inhibitor, exhibits proliferation-inhibitory and anti-metastatic effects on A549 cells by modulating epithelial-mesenchymal transition (EMT) through the induction of ROS-mediated ERK/JNK signaling, achieved by inhibiting TrxR1 enzyme activity. The efficacy of CPUL1 is enhanced when used in conjunction with α-Lipoic Acid or Dithiodipropionic acid [1].

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Others

2043576

C22H13Cl2N5O

434.28

C(#N)C=1C(C2=C3C(N=C4C(=N3)C=CC=C4)=CC(N)=C2OC1N)C5=CC(Cl)=C(Cl)C=C5

-20°C

Ice Packs

Small Compound